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Anti-Human DNAH17 Polyclonal Antibody (HA847014)

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Overview
Catalog No.HA847014
Description
Anti-Human DNAH17 Polyclonal Antibody (HA847014) is a rabbit polyclonal antibody detecting DNAH17 in ELISA, IHC, WB. Suitable for Human.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
Species reactivityHuman, Mouse
ApplicationsELISA, IHC, WB
Host speciesRabbit
IsotypeIgG
Clonality Polyclonal
Immunogen E. coli - derived recombinant Human DNAH17 (Leu4347-Glu4446).
Target DNAHL1, Ciliary dynein heavy chain 17, Axonemal dynein heavy chain-like protein 1, Ciliary dynein heavy chain-like protein 1, Dynein light chain 2, axonemal, DNAH17, Axonemal beta dynein heavy chain 17, DNEL2, Dynein heavy chain 17, axonemal
Purification Purified by antigen affinity column.
Accession Q9UFH2
Form Liquid
Storage buffer 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Product Usage Information
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Stability and Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Background

Dynein axonemal heavy chain 17 (DNAH17) is a ~509 kDa protein. Force generating protein component of the outer dynein arms (ODAs) in the sperm flagellum. Produces force towards the minus ends of microtubules. Key component of dynein, a family of motor proteins essential for movement along microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP. Required for structural and functional integrity of cilia.

1. Whitfield, M. et al. (2019) American journal of human genetics 105, 198-212. PMID: 31178125
Note For research use only.
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Datasheet
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Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
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Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
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V₁ (Stock Vol.)
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Working Solution
C₂ (Working Conc.)
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V₂ (Working Vol.)
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Anti-Human DNAH17 Polyclonal Antibody

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