

| Catalog No. | HB928014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Species reactivity | Human | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Host species | Rabbit | ||||||||
| Clonality | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogen | E. coli - derived recombinant Human DPEP1 (Asp17-Leu411). | ||||||||
| Target | Renal dipeptidase, Dipeptidase 1, Beta-lactamase, DPEP1, MDP, RDP, Microsomal dipeptidase, hRDP, Dehydropeptidase-I | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Accession | P16444 | ||||||||
| Form | Liquid | ||||||||
| Storage buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Background | Dipeptidase 1 (DPEP1) is a ~45 kDa protein. Hydrolyzes a wide range of dipeptides including the conversion of leukotriene D4 to leukotriene E4. Hydrolyzes cystinyl-bis-glycine (cys-bis-gly) formed during glutathione degradation. Also possesses beta lactamase activity and can hydrolyze the beta-lactam antibiotic imipenem. 1. Adachi, H. et al. (1990) The Journal of biological chemistry 265, 3992-5. PMID: 2303490 2. Choudhury, SR. et al. (2019) Cell 178, 1205-1221.e17. PMID: 31442408 3. Hayashi, K. et al. (2020) Journal of structural biology 211, 107512. PMID: 32325220 4. Campbell, BJ. et al. (1984) The Journal of biological chemistry 259, 14586-90. PMID: 6334084 | ||||||||
| Note | For research use only. |
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