Anti-Human DRD3 Recombinant Antibody (N331/19) (HW393013)

Name: Anti-Human DRD3 Recombinant Antibody (N331/19)
Brand: abinScience
SKU: HW393013
Price: 126 USD
Availability: InStock

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Overview
Images
References
Datasheet
SDS

Overview

Catalog No.

HW393013

Description

Anti-Human DRD3 Recombinant Antibody (N331/19) (HW393013) is a mouse monoclonal antibody detecting DRD3/Dopamine D3 receptor in ICC, IHC, WB. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

Species reactivity

Human

Applications

ICC, IHC, WB

Host species

Mouse

Clonality

Monoclonal

Isotype

IgG2a, kappa

Clone ID

N331/19

Target

D(3) dopamine receptor, Dopamine D3 receptor, DRD3

Endotoxin level

< 10 EU/mg as determined by LAL method.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P35462

Form

Liquid

Storage buffer

0.01M PBS pH 7.4.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Background

D(3) dopamine receptor (DRD3/Dopamine D3 receptor) is a ~44 kDa protein. Dopamine receptor that is primarily expressed in limbic areas of the brain and is involved in the modulation of cognitive, emotional, and endocrine functions. Plays a key role in regulating neuronal signaling pathways associated with motivation, reward, and behavior. Coupled to G(i)/G(o) proteins; activation leads to inhibition of adenylate cyclase and decreased intracellular cAMP levels. Involved in the control of locomotor activity and implicated in several neuropsychiatric disorders, including schizophrenia and substance use disorders. Promotes cell proliferation through MAP kinase signaling.

1. Osugo, M. et al. (2025) Nature communications 16, 1852. PMID: 39984436

2. Zaworski, PG. et al. (1999) British journal of pharmacology 128, 1181-8. PMID: 10578130

3. Villar, VA. et al. (2009) The Journal of biological chemistry 284, 21425-34. PMID: 19520868

4. Barroso-Chinea, P. et al. (2020) Autophagy 16, 1279-1295. PMID: 31538542

Note

For research use only.

Isotype Control

Mouse IgG2a Recombinant Isotype Control Antibody (S43.10) (MF533307)

Images

Bioactivity

SEC-HPLC detection for Anti-Human DRD3 Antibody (N331/19).
SDS-PAGE

SDS-PAGE for Anti-Human DRD3 Antibody (N331/19).

References

Datasheet

Anti-Human DRD3 Recombinant Antibody (N331/19).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-Human DRD3 Recombinant Antibody (N331/19) (HW393013)

Overview

Images

References

Datasheet

SDS