Anti-Human DST/Dystonin Polyclonal Antibody (HX101034)

Name: Anti-Human DST/Dystonin Polyclonal Antibody
Brand: abinScience
SKU: HX101034
Price: 96 USD
Availability: InStock

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Overview
Images
References
Datasheet
SDS

Overview

Catalog No.

HX101034

Description

Anti-Human DST/Dystonin Polyclonal Antibody (HX101034) is a rabbit polyclonal antibody detecting Dystonin in ELISA, IHC, WB. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

Species reactivity

Human, Mouse

Applications

ELISA, IHC, WB

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human DST/Dystonin (Lys580-Glu803).

Target

Dystonin, 230 kDa bullous pemphigoid antigen, 230/240 kDa bullous pemphigoid antigen, Bullous pemphigoid antigen 1, BPA, Bullous pemphigoid antigen, Dystonia musculorum protein, Hemidesmosomal plaque protein, DST, BP230, BP240, BPAG1, DMH, DT, KIAA0728

Purification

Purified by antigen affinity column.

Accession

Q03001

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Dystonin (DST) is a ~860 kDa protein. Cytoskeletal linker protein. Acts as an integrator of intermediate filaments, actin and microtubule cytoskeleton networks. Required for anchoring either intermediate filaments to the actin cytoskeleton in neural and muscle cells or keratin-containing intermediate filaments to hemidesmosomes in epithelial cells. The proteins may self-aggregate to form filaments or a two-dimensional mesh. Regulates the organization and stability of the microtubule network of sensory neurons to allow axonal transport.

Note

For research use only.

Images

Western blot

Western blot analysis was performed using anti-DST polyclonal antibody at 1ug/mL on various samples.
Lane 1: Rat brain lysate
Lane 2: Rat eye lysate