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Anti-Human DUSP29 Polyclonal Antibody (HD314014)

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Overview
Catalog No.HD314014
Description
Anti-Human DUSP29 Polyclonal Antibody (HD314014) is a rabbit polyclonal antibody detecting DUSP29. Suitable for Human.
Species reactivityHuman
ApplicationsELISA, IHC, WB
Host speciesRabbit
IsotypeIgG
Clonality Polyclonal
Immunogen E. coli - derived recombinant Human DUSP29 (Thr35-Leu220).
Target DUPD1, DUSP27, DUSP29, Dual specificity phosphatase 27, Dual specificity phosphatase 29, Dual specificity phosphatase DUPD1, EC:3.1.3.16, EC:3.1.3.48
Endotoxin level Please contact with the lab for this information.
Purification Purified by antigen affinity column.
Accession Q68J44
Form Liquid
Storage buffer 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Product Usage Information
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Background

Dual specificity phosphatase 29 (DUSP29) is a ~25 kDa protein. Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues within the same substrate, with a preference for phosphotyrosine as a substrate. Involved in the modulation of intracellular signaling cascades. In skeletal muscle regulates systemic glucose homeostasis by activating, AMPK, an energy sensor protein kinase. Affects MAP kinase signaling though modulation of the MAPK1/2 cascade in skeletal muscle promoting muscle cell differentiation, development and atrophy.

1. Friedberg, I. et al. (2007) FEBS letters 581, 2527-33. PMID: 17498703
Note For research use only
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Formula
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Anti-Human DUSP29 Polyclonal Antibody

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