

| Catalog No. | HT407014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-Human DYNC1I1 Polyclonal Antibody (HT407014) is a rabbit polyclonal antibody detecting DYNC1I1 in ELISA, IHC, WB. Suitable for Human.
Highlights
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| Species reactivity | Human, Mouse, Rat | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Host species | Rabbit | ||||||||
| Clonality | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogen | E. coli - derived recombinant Human DYNC1I1 (Leu273-Gly608). | ||||||||
| Target | Cytoplasmic dynein 1 intermediate chain 1, Cytoplasmic dynein intermediate chain 1, Dynein intermediate chain 1, cytosolic, DH IC-1, DYNC1I1, DNCI1, DNCIC1 | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Accession | O14576 | ||||||||
| Form | Liquid | ||||||||
| Storage buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Background | Cytoplasmic dynein 1 intermediate chain 1 (DYNC1I1) is a ~72 kDa protein. Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. The intermediate chains mediate the binding of dynein to dynactin via its 150 kDa component (p150-glued) DCTN1. May play a role in mediating the interaction of cytoplasmic dynein with membranous organelles and kinetochores. | ||||||||
| Note | For research use only. |
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