

| Catalog No. | HB815013 | ||||
|---|---|---|---|---|---|
| Description |
Anti-Human EPHB2 Recombinant Antibody (SAA1617) (HB815013) is a mouse monoclonal antibody detecting EPHB2 in ELISA. Suitable for Human.
Highlights
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| Species reactivity | Human | ||||
| Applications | ELISA | ||||
| Host species | Mouse | ||||
| Clonality | Monoclonal | ||||
| Isotype | IgG2a, kappa | ||||
| Clone ID | SAA1617 | ||||
| Target | EPHT3, EPTH3, ERK, Developmentally-regulated Eph-related tyrosine kinase, Tyrosine-protein kinase receptor EPH-3, hEK5, Ephrin type-B receptor 2, Tyrosine-protein kinase TYRO5, EK5, HEK5, EPHB2, ELK-related tyrosine kinase, TYRO5, Renal carcinoma antigen NY-REN-47, EPH tyrosine kinase 3, DRT, EPH-like kinase 5 | ||||
| Endotoxin level | < 10 EU/mg as determined by LAL method. | ||||
| Purity | >95% as determined by SDS-PAGE. | ||||
| Purification | Protein A/G purified from cell culture supernatant. | ||||
| Accession | P29323 | ||||
| RRID | Anti-Human EPHB2 Antibody (SAA1617) (abinScience Cat# HB815013, RRID:AB_3727378) |
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| Form | Liquid | ||||
| Storage buffer | 0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. | ||||
| Background | Ephrin type-B receptor 2 (EPHB2) is a ~117 kDa protein. Receptor tyrosine kinase which binds promiscuously transmembrane ephrin-B family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Functions in axon guidance during development. Involved in the guidance of commissural axons, that form a major interhemispheric connection between the 2 temporal lobes of the cerebral cortex. Also involved in guidance of contralateral inner ear efferent growth cones at the midline and of retinal ganglion cell axons to the optic disk. 1. Berrou, E. et al. (2018) Blood 132, 2067-2077. PMID: 30213874 | ||||
| Note | For research use only. |

SDS-PAGE for Anti-Human EPHB2 Antibody (SAA1617)
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