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Anti-Human EPHB2 Recombinant Antibody (SAA1617) (HB815013)

Anti-Human EPHB2 Recombinant Antibody (SAA1617)
Anti-Human EPHB2 Recombinant Antibody (SAA1617)
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Overview
Catalog No.HB815013
Species reactivityHuman
ApplicationsELISA
Host speciesMouse
IsotypeIgG2a, kappa
Clone IDSAA1617
Clonality Monoclonal
Target EPHT3, EPTH3, ERK, Developmentally-regulated Eph-related tyrosine kinase, Tyrosine-protein kinase receptor EPH-3, hEK5, Ephrin type-B receptor 2, Tyrosine-protein kinase TYRO5, EK5, HEK5, EPHB2, ELK-related tyrosine kinase, TYRO5, Renal carcinoma antigen NY-REN-47, EPH tyrosine kinase 3, DRT, EPH-like kinase 5
Endotoxin level Please contact with the lab for this information.
Purity >95% as determined by SDS-PAGE.
Purification Protein A/G purified from cell culture supernatant.
Accession P29323
RRID Anti-Human EPHB2 Antibody (SAA1617) (abinScience Cat# HB815013, RRID:AB_3727378)
Form Liquid
Storage buffer 0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information
Application Dilution
ELISA 1:2000-1:20000
Stability and Storage Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Background

Ephrin type-B receptor 2 (EPHB2) is a ~117 kDa protein. Receptor tyrosine kinase which binds promiscuously transmembrane ephrin-B family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Functions in axon guidance during development. Involved in the guidance of commissural axons, that form a major interhemispheric connection between the 2 temporal lobes of the cerebral cortex. Also involved in guidance of contralateral inner ear efferent growth cones at the midline and of retinal ganglion cell axons to the optic disk.

1. Berrou, E. et al. (2018) Blood 132, 2067-2077. PMID: 30213874
Note For research use only.
Images
  • Anti-Human EPHB2 Recombinant Antibody (SAA1617)

    SDS-PAGE

    SDS-PAGE for Anti-Human EPHB2 Antibody (SAA1617)

References
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
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Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
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V₁ (Stock Vol.)
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Working Solution
C₂ (Working Conc.)
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V₂ (Working Vol.)
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