Anti-Human Erythropoietin R Recombinant Nanobody (SAA0954) (HB152023)

Name: Anti-Human Erythropoietin R Recombinant Nanobody (SAA0954)
Brand: abinScience
SKU: HB152023
Price: 126 USD
Availability: InStock

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Overview
Images
References
Datasheet
SDS

Overview

Catalog No.

HB152023

Description

Anti-Human EPOR Nanobody (SAA0954) [SAA0954] (HB152023) is a alpaca monoclonal antibody detecting EPOR in ELISA. Suitable for Human.

Species reactivity

Human

Applications

ELISA

Host species

Alpaca

Clonality

Monoclonal

Isotype

VHH-8His-Cys-tag

Clone ID

SAA0954

Target

EPOR, Erythropoietin receptor, EPO-R

Endotoxin level

< 10 EU/mg as determined by LAL method.

Purity

>95% as determined by SDS-PAGE.

Purification

Purified by Nickel column.

Accession

P19235

Form

Liquid

Storage buffer

0.01M PBS pH 7.4.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:2000-1:20000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Erythropoietin receptor (EPOR) is a ~55 kDa protein. Receptor for erythropoietin, which mediates erythropoietin-induced erythroblast proliferation and differentiation. Upon EPO stimulation, EPOR dimerizes triggering the JAK2/STAT5 signaling cascade. In some cell types, can also activate STAT1 and STAT3. May also activate the LYN tyrosine kinase.

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1. Zhan, H. et al. (1999) Protein engineering 12, 505-13. PMID: 10388848

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2. Winkelmann, JC. et al. (1990) Blood 76, 24-30. PMID: 2163695

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3. Jones, SS. et al. (1990) Blood 76, 31-5. PMID: 2163696

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4. Middleton, SA. et al. (1996) The Journal of biological chemistry 271, 14045-54. PMID: 8662939

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5. Syed, RS. et al. (1998) Nature 395, 511-6. PMID: 9774108

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6. Kirito, K. et al. (2002) Blood 99, 102-10. PMID: 11756159

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Note

For research use only.

Images

SDS-PAGE

SDS-PAGE for Anti-Human EPOR Nanobody (SAA0954)
Bioactivity

Detects recombinant human EPOR (Catalog No: HB152011) in indirect ELISA

References

Datasheet

Anti-Human Erythropoietin R Recombinant Nanobody (SAA0954).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-Human Erythropoietin R Recombinant Nanobody (SAA0954) (HB152023)

Overview

Images

References

Datasheet

SDS