Anti-Human FAAH Polyclonal Antibody (HD694014)

Name: Anti-Human FAAH Polyclonal Antibody
Brand: abinScience
SKU: HD694014
Price: 168 USD
Availability: InStock

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Datasheet
SDS

Overview

Catalog No.

HD694014

Description

Anti-Human FAAH Polyclonal Antibody (HD694014) is a rabbit polyclonal antibody detecting FAAH. Suitable for Human.

Species reactivity

Human

Applications

ELISA, IHC, WB

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human FAAH (Ser71-Ser579).

Target

Anandamide amidohydrolase 1, EC:3.1.1.-, EC:3.5.1.99, FAAH, FAAH1, Fatty acid ester hydrolase, Fatty-acid amide hydrolase 1, Oleamide hydrolase 1

Endotoxin level

Please contact with the lab for this information.

Purification

Purified by antigen affinity column.

Accession

O00519

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Background

Fatty-acid amide hydrolase 1 (FAAH) is a ~63 kDa protein. Catalyzes the hydrolysis of endogenous amidated lipids like the sleep-inducing lipid oleamide ((9Z)-octadecenamide), the endocannabinoid anandamide (N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-ethanolamine), as well as other fatty amides, to their corresponding fatty acids, thereby regulating the signaling functions of these molecules. Hydrolyzes polyunsaturated substrate anandamide preferentially as compared to monounsaturated substrates. It can also catalyze the hydrolysis of the endocannabinoid 2-arachidonoylglycerol (2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-glycerol). FAAH cooperates with PM20D1 in the hydrolysis of amino acid-conjugated fatty acids such as N-fatty acyl glycine and N-fatty acyl-L-serine, thereby acting as a physiological regulator of specific subsets of intracellular, but not of extracellular, N-fatty acyl amino acids.

1. Wei, BQ. et al. (2006) The Journal of biological chemistry 281, 36569-78. PMID: 17015445

2. Kaczocha, M. et al. (2010) The Journal of biological chemistry 285, 2796-806. PMID: 19926788

3. Giang, DK. et al. (1997) Proceedings of the National Academy of Sciences of the United States of America 94, 2238-42. PMID: 9122178

4. Xie, S. et al. (2010) Chemical research in toxicology 23, 1890-904. PMID: 21049984

Note

For research use only

Images

References

Datasheet

Anti-Human FAAH Polyclonal Antibody.pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-Human FAAH Polyclonal Antibody (HD694014)

Overview

Images

References

Datasheet

SDS

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