Anti-Human FALZ/BPTF IP Recombinant Antibody (SAA0188) (HC673013)

Name: Anti-Human FALZ/BPTF IP Recombinant Antibody (SAA0188)
Brand: abinScience
SKU: HC673013
Price: 191 USD
Availability: InStock

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50ug
100ug
1mg

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Overview
Images
References
Datasheet
SDS

Overview

Catalog No.

HC673013

Species reactivity

Human, Mouse

Applications

ELISA, IF, IP

Host species

Mouse

Isotype

IgG

Clone ID

SAA0188

Clonality

Monoclonal

Target

Fetal Alzheimer antigen, FALZ, Nucleosome-remodeling factor subunit BPTF, FAC1, BPTF, Fetal Alz-50 clone 1 protein, Bromodomain and PHD finger-containing transcription factor

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

Q12830

RRID

Anti-Human FALZ/BPTF IP Antibody (SAA0188) (abinScience Cat# HC673013, RRID:AB_3729722)

Form

Liquid

Storage buffer

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:2000-1:20000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Background

Nucleosome-remodeling factor subunit BPTF (FALZ) is a ~338 kDa protein. Regulatory subunit of the ATP-dependent NURF-1 and NURF-5 ISWI chromatin remodeling complexes, which form ordered nucleosome arrays on chromatin and facilitate access to DNA during DNA-templated processes such as DNA replication, transcription, and repair. The NURF-1 ISWI chromatin remodeling complex has a lower ATP hydrolysis rate than the NURF-5 ISWI chromatin remodeling complex. Within the NURF-1 ISWI chromatin-remodeling complex, binds to the promoters of En1 and En2 to positively regulate their expression and promote brain development. Histone-binding protein which binds to H3 tails trimethylated on 'Lys-4' (H3K4me3), which mark transcription start sites of active genes. Binds to histone H3 tails dimethylated on 'Lys-4' (H3K4Me2) to a lesser extent.

1. Barak, O. et al. (2003) The EMBO journal 22, 6089-100. PMID: 14609955

2. Oppikofer, M. et al. (2017) EMBO reports 18, 1697-1706. PMID: 28801535

3. Wysocka, J. et al. (2006) Nature 442, 86-90. PMID: 16728976

4. Li, H. et al. (2006) Nature 442, 91-5. PMID: 16728978

5. Li, H. et al. (2007) Molecular cell 28, 677-91. PMID: 18042461

6. Jordan-Sciutto, KL. et al. (1999) The Journal of biological chemistry 274, 35262-8. PMID: 10575013

Note

For research use only.

Images

SDS-PAGE

SDS-PAGE for Anti-Human FALZ/BPTF IP Antibody (SAA0188)

References

Datasheet

Anti-Human FALZ/BPTF IP Recombinant Antibody (SAA0188).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-Human FALZ/BPTF IP Recombinant Antibody (SAA0188) (HC673013)

Overview

Images

References

Datasheet

SDS

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