

| Catalog No. | HP091014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-Human FASTKD2 Polyclonal Antibody (HP091014) is a rabbit polyclonal antibody detecting FASTKD2 in ELISA, IHC, WB. Suitable for Human and Pongo abelii.
Highlights
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| Species reactivity | Human | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Host species | Rabbit | ||||||||
| Clonality | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogen | E. coli - derived recombinant Human FASTKD2 (Lys471-Ser695). | ||||||||
| Target | KIAA0971, FAST kinase domain-containing protein 2, mitochondrial, FASTKD2 | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Accession | Q9NYY8 | ||||||||
| Form | Liquid | ||||||||
| Storage buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Background | FAST kinase domain-containing protein 2, mitochondrial (FASTKD2) is a ~81 kDa protein. Plays an important role in assembly of the mitochondrial large ribosomal subunit. As a component of a functional protein-RNA module, consisting of RCC1L, NGRN, RPUSD3, RPUSD4, TRUB2, FASTKD2 and 16S mitochondrial ribosomal RNA (16S mt-rRNA), controls 16S mt-rRNA abundance and is required for intra-mitochondrial translation. May play a role in mitochondrial apoptosis. 1. Antonicka, H. et al. (2015) Cell reports 10, 920-932. PMID: 25683715 2. Popow, J. et al. (2015) RNA (New York, N.Y.) 21, 1873-84. PMID: 26370583 3. Arroyo, JD. et al. (2016) Cell metabolism 24, 875-885. PMID: 27667664 | ||||||||
| Note | For research use only. |
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