

| Catalog No. | HD229014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-Human FASTKD3 Polyclonal Antibody (HD229014) is a rabbit polyclonal antibody detecting FASTKD3. Suitable for Human.
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| Species reactivity | Human | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Host species | Rabbit | ||||||||
| Isotype | IgG | ||||||||
| Clonality | Polyclonal | ||||||||
| Immunogen | E. coli - derived recombinant Human FASTKD3 (Val84-Tyr516). | ||||||||
| Target | FAST kinase domain-containing protein 3, mitochondrial, FASTKD3 | ||||||||
| Endotoxin level | Please contact with the lab for this information. | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Accession | Q14CZ7 | ||||||||
| Form | Liquid | ||||||||
| Storage buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Background | FAST kinase domain-containing protein 3, mitochondrial (FASTKD3) is a ~75 kDa protein. Required for normal mitochondrial respiration. Increases steady-state levels and half-lives of a subset of mature mitochondrial mRNAs MT-ND2, MT-ND3, MT-CYTB, MT-CO2, and MT-ATP8/6. Promotes MT-CO1 mRNA translation and increases mitochondrial complex IV assembly and activity. 1. Simarro, M. et al. (2010) Biochemical and biophysical research communications 401, 440-6. PMID: 20869947 2. Boehm, E. et al. (2016) The Journal of biological chemistry 291, 25877-25887. PMID: 27789713 | ||||||||
| Note | For research use only |
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