

| Catalog No. | HD590014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-Human FDPS Polyclonal Antibody (HD590014) is a rabbit polyclonal antibody detecting FDPS. Suitable for Human.
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| Species reactivity | Human | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Host species | Rabbit | ||||||||
| Isotype | IgG | ||||||||
| Clonality | Polyclonal | ||||||||
| Immunogen | E. coli - derived recombinant Human FDPS (Asp74-Lys419). | ||||||||
| Target | (2E,6E)-farnesyl diphosphate synthase, Dimethylallyltranstransferase, EC:2.5.1.1, EC:2.5.1.10, FDPS, FPP synthase, FPS, Farnesyl diphosphate synthase, Farnesyl pyrophosphate synthase, Geranyltranstransferase, KIAA1293 | ||||||||
| Endotoxin level | Please contact with the lab for this information. | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Accession | P14324 | ||||||||
| Form | Liquid | ||||||||
| Storage buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Background | Farnesyl pyrophosphate synthase (FDPS) is a ~48 kDa protein. Key enzyme in isoprenoid biosynthesis which catalyzes the formation of farnesyl diphosphate (FPP), a precursor for several classes of essential metabolites including sterols, dolichols, carotenoids, and ubiquinones. FPP also serves as substrate for protein farnesylation and geranylgeranylation. Catalyzes the sequential condensation of isopentenyl pyrophosphate with the allylic pyrophosphates, dimethylallyl pyrophosphate, and then with the resultant geranylpyrophosphate to the ultimate product farnesyl pyrophosphate. | ||||||||
| Note | For research use only |

Western blot analysis was performed using anti-FDPS polyclonal antibody at 1ug/mL on various samples.
Lane 1: Jurkat cell lysate
Lane 2: Hela cell lysate
Lane 3: N2A cell lysate
Lane 4: NIH3T3 cell lysate
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