

| Catalog No. | HA324014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-Human FGD5 Polyclonal Antibody (HA324014) is a rabbit polyclonal antibody detecting FGD5 in ELISA, IHC, WB. Suitable for Human.
Highlights
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| Species reactivity | Human | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Host species | Rabbit | ||||||||
| Clonality | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogen | E. coli - derived recombinant Human FGD5 (Arg892-Arg1035). | ||||||||
| Target | Zinc finger FYVE domain-containing protein 23, FGD5, FYVE, RhoGEF and PH domain-containing protein 5, ZFYVE23 | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Accession | Q6ZNL6 | ||||||||
| Form | Liquid | ||||||||
| Storage buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Background | FYVE, RhoGEF and PH domain-containing protein 5 (FGD5) is a ~159 kDa protein. Activates CDC42, a member of the Ras-like family of Rho- and Rac proteins, by exchanging bound GDP for free GTP. Mediates VEGF-induced CDC42 activation. May regulate proangiogenic action of VEGF in vascular endothelial cells, including network formation, directional movement and proliferation. May play a role in regulating the actin cytoskeleton and cell shape. | ||||||||
| Note | For research use only. |
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