Anti-Human FGF1/aFGF Recombinant Antibody (SAA0436) (HY232107)

Name: Anti-Human FGF1/aFGF Recombinant Antibody (SAA0436)
Brand: abinScience
SKU: HY232107
Price: 196 USD
Availability: InStock

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Overview

Catalog No.	HY232107
Species reactivity	Human
Applications	ELISA, FCM
Host species	Mouse
Isotype	IgG2a, kappa
Clone ID	SAA0436
Clonality	Monoclonal
Target	Endothelial cell growth factor, HBGF-1, Fibroblast growth factor 1, FGF1, ECGF, Acidic fibroblast growth factor, aFGF, Heparin-binding growth factor 1, FGF-1, FGFA
Endotoxin level	Please contact with the lab for this information.
Purity	>95% as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Accession	P05230
Form	Liquid
Storage buffer	0.01M PBS, pH 7.4, 0.09% Sodium azide. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Background	Fibroblast growth factor 1 (FGF1/aFGF) is a ~17 kDa protein. Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as a potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrin ITGAV:ITGB3. 1. Mori, S. et al. (2008) The Journal of biological chemistry 283, 18066-75. PMID: 18441324 2. Yamaji, S. et al. (2010) PloS one 5, e10273. PMID: 20422052 3. Mori, S. et al. (2013) PloS one 8, e57927. PMID: 23469107
Note	For research use only.

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SDS-PAGE for Anti-Human FGF1/aFGF Antibody (SAA0436)

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Datasheet

Anti-Human FGF1/aFGF Recombinant Antibody (SAA0436).pdf

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Anti-Human FGF1/aFGF Recombinant Antibody (SAA0436) (HY232107)

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