Anti-Human FLII Polyclonal Antibody (HC469014)

Name: Anti-Human FLII Polyclonal Antibody
Brand: abinScience
SKU: HC469014
Price: 96 USD
Availability: InStock

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Overview
Images
References
Datasheet
SDS

Overview

Catalog No.

HC469014

Description

Anti-Human FLII Polyclonal Antibody (HC469014) is a rabbit polyclonal antibody detecting FLII in ELISA, IHC, WB. Suitable for Mus musculus and Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

Species reactivity

Human

Applications

ELISA, IHC, WB

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human FLII (Leu896-Phe1176).

Target

FLII

Purification

Purified by antigen affinity column.

Accession

Q13045

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Alternate Names

Protein flightless-1 homolog, FLII, FLIL

Background

Protein flightless-1 homolog (FLII) is a ~144 kDa protein. Is a regulator of actin polymerization, required for proper myofibril organization and regulation of the length of sarcomeric thin filaments. It also plays a role in the assembly of cardiomyocyte cell adhesion complexes. Regulates cytoskeletal rearrangements involved in cytokinesis and cell migration, by inhibiting Rac1-dependent paxillin phosphorylation. May play a role as coactivator in transcriptional activation by hormone-activated nuclear receptors (NR) and acts in cooperation with NCOA2 and CARM1. Involved in estrogen hormone signaling.

1. Lee, YH. et al. (2004) Molecular and cellular biology 24, 2103-17. PMID: 14966289

Note

For research use only.

Images

Western blot

Western blot analysis was performed using anti-FLII polyclonal antibody at 1ug/mL on various samples.
Lane 1: HepG2 cell lysate
Lane 2: A549 cell lysate