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Anti-Human FLNC Polyclonal Antibody (HC548014)

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Overview
Catalog No.HC548014
Description
Anti-Human FLNC Polyclonal Antibody (HC548014) is a rabbit polyclonal antibody detecting FLNC. Suitable for Rat, Mouse, and Human.
Highlights
  • Multi-Species — Cross-reactive for translational research.
Species reactivityHuman, Mouse, Rat
ApplicationsELISA, IHC, WB
Host speciesRabbit
IsotypeIgG
Clonality Polyclonal
Immunogen E. coli - derived recombinant Human FLNC (Glu17-Lys259).
Target ABP-280-like protein, ABP-L, ABPL, Actin-binding-like protein, FLN-C, FLN2, FLNC, FLNc, Filamin-2, Filamin-C, Gamma-filamin
Endotoxin level Please contact with the lab for this information.
Purification Purified by antigen affinity column.
Accession Q14315
Form Liquid
Storage buffer 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Background

Filamin-C (FLNC) is a ~291 kDa protein. Muscle-specific filamin, which plays a central role in sarcomere assembly and organization. Critical for normal myogenesis, it probably functions as a large actin-cross-linking protein with structural functions at the Z lines in muscle cells. May be involved in reorganizing the actin cytoskeleton in response to signaling events.

1. Agarwal, R. et al. (2021) Circulation research 129, 751-766. PMID: 34405687
Note For research use only
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Formula
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Formula
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