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Anti-Human FLT1 Monoclonal Antibody (1A118) (HB265165)

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Anti-Human FLT1 Monoclonal Antibody (1A118)

Anti-Human FLT1 Monoclonal Antibody (1A118)

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Overview

Catalog No.	HB265165
Description	Anti-Human FLT1 Monoclonal Antibody (1A118) [1A118] (HB265165) is a mouse monoclonal antibody detecting FLT1 in ELISA, IHC, WB. Suitable for Human. Highlights ●Recombinant — Superior batch-to-batch reproducibility with defined sequences. ●Multi-Application — Validated across multiple applications.
Species reactivity	Human
Applications	ELISA, IHC, WB
Host species	Mouse
Isotype	IgG1
Clone ID	1A118
Clonality	Monoclonal
Immunogen	Mammalian cells - derived recombinant Human FLT1 (Met1-Ile328).
Target	FLT1, Vascular endothelial growth factor receptor 1, VEGFR1, Vascular permeability factor receptor, FRT, Tyrosine-protein kinase receptor FLT, VEGFR-1, FLT, FLT-1, Tyrosine-protein kinase FRT, Fms-like tyrosine kinase 1
Purification	Protein A/G purified from cell culture supernatant.
Accession	P17948
Form	Liquid
Storage buffer	0.01M PBS, pH 7.4. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Background	Vascular endothelial growth factor receptor 1 (FLT1/VEGFR1) is a ~150 kDa protein. Tyrosine-protein kinase that acts as a cell-surface receptor for VEGFA, VEGFB and PGF, and plays an essential role in the development of embryonic vasculature, the regulation of angiogenesis, cell survival, cell migration, macrophage function, chemotaxis, and cancer cell invasion. Acts as a positive regulator of postnatal retinal hyaloid vessel regression. May play an essential role as a negative regulator of embryonic angiogenesis by inhibiting excessive proliferation of endothelial cells. Can promote endothelial cell proliferation, survival and angiogenesis in adulthood. Its function in promoting cell proliferation seems to be cell-type specific. 1. Lesslie, DP. et al. (2006) British journal of cancer 94, 1710-7. PMID: 16685275
Note	For research use only.

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SDS-PAGE for Anti-Human FLT1 Monoclonal Antibody (1A118)

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Datasheet

Anti-Human FLT1 Monoclonal Antibody (1A118).pdf

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Anti-Human FLT1 Monoclonal Antibody (1A118)