

| Catalog No. | HB265195 |
|---|---|
| Description |
Anti-Human FLT1/VEGFR1 Monoclonal Antibody (1A418) [1A418] (HB265195) is a mouse monoclonal antibody detecting VEGFR1 in ELISA. Suitable for Human.
|
| Species reactivity | Human |
| Applications | ELISA |
| Host species | Mouse |
| Isotype | IgG |
| Clone ID | 1A418 |
| Clonality | Monoclonal |
| Immunogen | Human FLT1/VEGFR1 Protein. |
| Target | Vascular endothelial growth factor receptor 1, VEGFR-1, 2.7.10.1, Fms-like tyrosine kinase 1, FLT-1, Tyrosine-protein kinase FRT, Tyrosine-protein kinase receptor FLT, FLT, Vascular permeability factor receptor, FLT1, FLT, FRT, VEGFR1 |
| Purification | Protein A/G purified from cell culture supernatant. |
| Accession | P17948 |
| Form | Liquid |
| Storage buffer | 0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Background | Vascular endothelial growth factor receptor 1 (FLT1/VEGFR1) is a ~150 kDa protein. Tyrosine-protein kinase that acts as a cell-surface receptor for VEGFA, VEGFB and PGF, and plays an essential role in the development of embryonic vasculature, the regulation of angiogenesis, cell survival, cell migration, macrophage function, chemotaxis, and cancer cell invasion. Acts as a positive regulator of postnatal retinal hyaloid vessel regression. May play an essential role as a negative regulator of embryonic angiogenesis by inhibiting excessive proliferation of endothelial cells. Can promote endothelial cell proliferation, survival and angiogenesis in adulthood. Its function in promoting cell proliferation seems to be cell-type specific. 1. Lesslie, DP. et al. (2006) British journal of cancer 94, 1710-7. PMID: 16685275 |
| Note | For research use only. |

SDS-PAGE for Anti-Human FLT1/VEGFR1 Monoclonal Antibody (1A418)




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