Anti-Human FOLR1 Recombinant Nanobody (SAA2797) (HB825023)

Name: Anti-Human FOLR1 Recombinant Nanobody (SAA2797)
Brand: abinScience
SKU: HB825023
Price: 191 USD
Availability: InStock

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Overview

Catalog No.	HB825023
Description	Anti-Human FOLR1 Nanobody (SAA2797) (HB825023) is a alpaca monoclonal antibody detecting Human FOLR1. Suitable for Human.
Species reactivity	Human
Applications	ELISA, FCM
Host species	Alpaca
Isotype	VHH-8His-Cys-tag
Clone ID	SAA2797
Clonality	Monoclonal
Target	ANPEP, AP-M, AP-N, APN, Alanyl aminopeptidase, Aminopeptidase M, Aminopeptidase N, CD13, EC:3.4.11.2, Microsomal aminopeptidase, Myeloid plasma membrane glycoprotein CD13, PEPN, gp150, hAPN
Endotoxin level	Please contact with the lab for this information.
Purity	>95% as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Accession	P15144
Form	Liquid
Storage buffer	0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Reconstitution	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Background	Aminopeptidase N (FOLR1) is a ~109 kDa protein. Broad specificity aminopeptidase which plays a role in the final digestion of peptides generated from hydrolysis of proteins by gastric and pancreatic proteases. Also involved in the processing of various peptides including peptide hormones, such as angiotensin III and IV, neuropeptides, and chemokines. May also be involved the cleavage of peptides bound to major histocompatibility complex class II molecules of antigen presenting cells. May have a role in angiogenesis and promote cholesterol crystallization. May have a role in amino acid transport by acting as binding partner of amino acid transporter SLC6A19 and regulating its activity. FOLR1 is the therapeutic target of mirvetuximab soravtansine (Elahere).
Note	For research use only