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Anti-Human FOXL2 Polyclonal Antibody (HX111014)

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Overview
Catalog No.HX111014
Species reactivityHuman, Mouse
ApplicationsELISA, IHC, WB
Host speciesRabbit
IsotypeIgG
Clonality Polyclonal
Immunogen E. coli - derived recombinant Human FOXL2 (Ser58-Gly141).
Target FOXL2, Forkhead box protein L2
Purification Purified by antigen affinity column.
Accession P58012
Form Liquid
Storage buffer 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Product Usage Information
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Stability and Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Background

Forkhead box protein L2 (FOXL2) is a ~38 kDa protein. Transcriptional regulator. Critical factor essential for ovary differentiation and maintenance, and repression of the genetic program for somatic testis determination. Prevents trans-differentiation of ovary to testis through transcriptional repression of the Sertoli cell-promoting gene SOX9. Has apoptotic activity in ovarian cells. Suppresses ESR1-mediated transcription of PTGS2/COX2 stimulated by tamoxifen.

Note For research use only.
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Formula
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V₁ (Stock Vol.)
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C₂ (Working Conc.)
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Anti-Human FOXL2 Polyclonal Antibody

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