Anti-Human FOXP1 Polyclonal Antibody (HV703014)

Name: Anti-Human FOXP1 Polyclonal Antibody
Brand: abinScience
SKU: HV703014
Price: 96 USD
Availability: InStock

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Overview
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References
Datasheet
SDS

Overview

Catalog No.

HV703014

Description

Anti-Human FOXP1 Polyclonal Antibody (HV703014) is a rabbit polyclonal antibody detecting FOXP1 in ELISA, IHC, WB. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

Species reactivity

Human, Mouse, Rat

Applications

ELISA, IHC, WB

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human FOXP1 (Asn461-Pro671).

Target

FOXP1, MFH, Forkhead box protein P1, Mac-1-regulated forkhead

Purification

Purified by antigen affinity column.

Accession

Q9H334

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Forkhead box protein P1 (FOXP1) is a ~75 kDa protein. Transcriptional repressor. Can act with CTBP1 to synergistically repress transcription but CTPBP1 is not essential. Plays an important role in the specification and differentiation of lung epithelium. Acts cooperatively with FOXP4 to regulate lung secretory epithelial cell fate and regeneration by restricting the goblet cell lineage program; the function may involve regulation of AGR2. Essential transcriptional regulator of B-cell development.

1. Jepsen, K. et al. (2008) Genes & development 22, 740-5. PMID: 18347093

2. Sollis, E. et al. (2016) Human molecular genetics 25, 546-57. PMID: 26647308

3. van Keimpema, M. et al. (2014) Blood 124, 3431-40. PMID: 25267198

4. Shi, C. et al. (2004) The Journal of clinical investigation 114, 408-18. PMID: 15286807

5. Shi, C. et al. (2008) Blood 112, 4699-711. PMID: 18799727

6. Grundmann, S. et al. (2013) PloS one 8, e70873. PMID: 24023716

7. Takayama, K. et al. (2008) Biochemical and biophysical research communications 374, 388-93. PMID: 18640093

8. Kamran, M. et al. (2017) Oncogenesis 6, e298. PMID: 28218735

Note

For research use only.

Images

Western blot

Western blot analysis was performed using anti-FOXP1 polyclonal antibody at 1ug/mL on various samples.
Lane 1: Jurkat cell lysate
Lane 2: MCF-7 cell lysate

References

Datasheet

Anti-Human FOXP1 Polyclonal Antibody.pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-Human FOXP1 Polyclonal Antibody (HV703014)

Overview

Images

References

Datasheet

SDS

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