Anti-Human FSHR Polyclonal Antibody (HB849014)

Name: Anti-Human FSHR Polyclonal Antibody
Brand: abinScience
SKU: HB849014
Price: 168 USD
Availability: InStock

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Overview
Images
References
Datasheet
SDS

Overview

Catalog No.

HB849014

Description

Anti-Human FSHR Polyclonal Antibody (HB849014) is a rabbit polyclonal antibody detecting FSHR in ELISA, IHC, WB. Suitable for Bovine, Cavia porcellus, Equus asinus, Equus caballus, and Cat.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

Species reactivity

Human

Applications

ELISA, IHC, WB

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human FSHR (Ser16-Lys349).

Target

Follicle-stimulating hormone receptor, FSH-R, Follitropin receptor, FSHR, LGR1

Purification

Purified by antigen affinity column.

Accession

P23945

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Follicle-stimulating hormone receptor (FSHR) is a ~78 kDa protein. G protein-coupled receptor for follitropin, the follicle-stimulating hormone. Through cAMP production activates the downstream PI3K-AKT and ERK1/ERK2 signaling pathways.

1. Costagliola, S. et al. (2002) The EMBO journal 21, 504-13. PMID: 11847099

2. Uchida, S. et al. (2013) PloS one 8, e75478. PMID: 24058690

3. Jiang, X. et al. (2014) The Journal of biological chemistry 289, 14273-82. PMID: 24692546

Note

For research use only.

Images

Western blot

Western blot analysis was performed using anti-Human FSHR polyclonal antibody at 1ug/mL on recombinant Human FSHR (Catalog No. HB849012).

References

Datasheet