

| Catalog No. | HC289014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-Human FSTL1 Polyclonal Antibody (HC289014) is a rabbit polyclonal antibody detecting FSTL1 in ELISA, IHC, WB. Suitable for Human.
Highlights
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| Species reactivity | Human | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Host species | Rabbit | ||||||||
| Isotype | IgG | ||||||||
| Clonality | Polyclonal | ||||||||
| Immunogen | E. coli - derived recombinant Human FSTL1 (Ser116-Thr266). | ||||||||
| Target | FSTL1, Follistatin-related protein 1, Follistatin-like protein 1, FRP, | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Accession | Q12841 | ||||||||
| Form | Liquid | ||||||||
| Storage buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Background | Follistatin-related protein 1 (FSTL1) is a ~34 kDa protein. Secreted glycoprotein that is involved in various physiological processes, such as angiogenesis, regulation of the immune response, cell proliferation and differentiation. Plays a role in the development of the central nervous system, skeletal system, lungs, and ureter. Promotes endothelial cell survival, migration and differentiation into network structures in an AKT-dependent manner. Also promotes survival of cardiac myocytes. Initiates various signaling cascades by activating different receptors on the cell surface such as DIP2A, TLR4 or BMP receptors. 1. Murakami, K. et al. (2012) FEBS letters 586, 319-24. PMID: 22265692 2. Jin, X. et al. (2017) Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 44, 1616-1628. PMID: 29212066 3. Ouchi, N. et al. (2010) The Journal of biological chemistry 285, 7127-34. PMID: 20054002 | ||||||||
| Note | For research use only. |

Western blot analysis was performed using anti-FSTL1 polyclonal antibody at 1ug/mL on various samples.
Lane 1: MCF-7 cell lysate



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