Anti-Human GABARAPL2 Polyclonal Antibody (HX995014)

Name: Anti-Human GABARAPL2 Polyclonal Antibody
Brand: abinScience
SKU: HX995014
Price: 168 USD
Availability: InStock

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Datasheet
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Overview

Catalog No.

HX995014

Description

Anti-Human GABARAPL2 Polyclonal Antibody (HX995014) is a rabbit polyclonal antibody detecting GABARAPL2 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat, and Bovine.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

Species reactivity

Human, Mouse, Rat

Applications

ELISA, IHC, WB

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human GABARAPL2 (Met1-Phe117).

Target

MAP1 light chain 3-related protein, GABA(A) receptor-associated protein-like 2, General protein transport factor p16, Ganglioside expression factor 2, GATE-16, GEF-2, GABARAPL2, Golgi-associated ATPase enhancer of 16 kDa, Gamma-aminobutyric acid receptor-associated protein-like 2, FLC3A, GEF2

Purification

Purified by antigen affinity column.

Accession

P60520

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Gamma-aminobutyric acid receptor-associated protein-like 2 (GABARAPL2) is a ~13 kDa protein. Ubiquitin-like modifier involved in intra-Golgi traffic. Modulates intra-Golgi transport through coupling between NSF activity and SNAREs activation. It first stimulates the ATPase activity of NSF which in turn stimulates the association with GOSR1. Involved in autophagy. Plays a role in mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production.

1. Weidberg, H. et al. (2010) The EMBO journal 29, 1792-802. PMID: 20418806

2. Zhu, Y. et al. (2013) The Journal of biological chemistry 288, 1099-113. PMID: 23209295

Note

For research use only.

Images

Western blot

Western blot analysis was performed using anti-Human GABARAPL2 polyclonal antibody at 1ug/mL on recombinant Human GABARAPL2 (Catalog No. HX995012).

References

Datasheet

Anti-Human GABARAPL2 Polyclonal Antibody.pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-Human GABARAPL2 Polyclonal Antibody (HX995014)

Overview

Images

References

Datasheet

SDS

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