

| Catalog No. | HD009014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-Human GAN Polyclonal Antibody (HD009014) is a rabbit polyclonal antibody detecting GAN. Suitable for Mouse and Human.
Highlights
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| Species reactivity | Human, Mouse | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Host species | Rabbit | ||||||||
| Isotype | IgG | ||||||||
| Clonality | Polyclonal | ||||||||
| Immunogen | E. coli - derived recombinant Human GAN (Gly270-Pro597). | ||||||||
| Target | GAN, GAN1, Gigaxonin, KLHL16, Kelch-like protein 16 | ||||||||
| Endotoxin level | Please contact with the lab for this information. | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Accession | Q9H2C0 | ||||||||
| Form | Liquid | ||||||||
| Storage buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Background | Gigaxonin (GAN) is a ~67 kDa protein. Probable cytoskeletal component that directly or indirectly plays an important role in neurofilament architecture. May act as a substrate-specific adapter of an E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Controls degradation of TBCB. Controls degradation of MAP1B and MAP1S, and is critical for neuronal maintenance and survival. | ||||||||
| Note | For research use only |
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