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Anti-Human GJB2 Recombinant Antibody (SAA1838) (HB148013)

Anti-Human GJB2 Recombinant Antibody (SAA1838)
Anti-Human GJB2 Recombinant Antibody (SAA1838)
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Overview
Catalog No.HB148013
Species reactivityHuman
ApplicationsELISA
Host speciesMouse
IsotypeIgG2a, kappa
Clone IDSAA1838
Clonality Monoclonal
Target Connexin-26, Cx26, GJB2, Gap junction beta-2 protein
Endotoxin level Please contact with the lab for this information.
Purity >95% as determined by SDS-PAGE.
Purification Protein A/G purified from cell culture supernatant.
Accession P29033
RRID

Anti-Human GJB2 Antibody (SAA1838) (abinScience Cat# HB148013, RRID:AB_3727601)
_x005F_x005F_x000D_

Form Liquid
Storage buffer 0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information
Application Dilution
ELISA 1:2000-1:20000
Stability and Storage Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Background

Gap junction beta-2 protein (GJB2) is a ~26 kDa protein. Structural component of gap junctions. Gap junctions are dodecameric channels that connect the cytoplasm of adjoining cells. They are formed by the docking of two hexameric hemichannels, one from each cell membrane. Small molecules and ions diffuse from one cell to a neighboring cell via the central pore.

1. Bicego, M. et al. (2006) Human molecular genetics 15, 2569-87. PMID: 16849369
2. Oshima, A. et al. (2007) Proceedings of the National Academy of Sciences of the United States of America 104, 10034-9. PMID: 17551008
3. Maeda, S. et al. (2009) Nature 458, 597-602. PMID: 19340074
4. Choi, SY. et al. (2009) Human mutation 30, E716-27. PMID: 19384972
5. Oshima, A. et al. (2011) Journal of molecular biology 405, 724-35. PMID: 21094651
6. Bennett, BC. et al. (2016) Nature communications 7, 8770. PMID: 26753910
Note For research use only.
Images
  • Anti-Human GJB2 Recombinant Antibody (SAA1838)

    SDS-PAGE

    SDS-PAGE for Anti-Human GJB2 Antibody (SAA1838)

References
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
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Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
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V₁ (Stock Vol.)
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Working Solution
C₂ (Working Conc.)
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V₂ (Working Vol.)
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