Anti-Human GLP-1R Recombinant Antibody (SAA0519) (HW328013)

Name: Anti-Human GLP-1R Recombinant Antibody (SAA0519)
Brand: abinScience
SKU: HW328013
Price: 126 USD
Availability: InStock

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Overview
Images
References
Datasheet
SDS

Overview

Catalog No.

HW328013

Description

Anti-Human GLP-1R Recombinant Antibody (SAA0519) (HW328013) is a mouse monoclonal antibody detecting GLP-1R in ELISA, IF, IHC. Suitable for Human, Monkey.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

Species reactivity

Human, Monkey

Applications

ELISA, IF, IHC

Host species

Mouse

Clonality

Monoclonal

Isotype

IgG2a, kappa

Clone ID

SAA0519

Target

GLP-1 receptor, Glucagon-like peptide 1 receptor, GLP1R, GLP-1-R, GLP-1R

Endotoxin level

< 10 EU/mg as determined by LAL method.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P43220

Form

Liquid

Storage buffer

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:2000-1:20000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Background

Glucagon-like peptide 1 receptor (GLP1R) is a ~53 kDa protein. G-protein coupled receptor for glucagon-like peptide 1 (GLP-1). Ligand binding triggers activation of a signaling cascade that leads to the activation of adenylyl cyclase and increased intracellular cAMP levels. Plays a role in regulating insulin secretion in response to GLP-1.

1. Underwood, CR. et al. (2010) The Journal of biological chemistry 285, 723-30. PMID: 19861722

2. Lau, J. et al. (2015) Journal of medicinal chemistry 58, 7370-80. PMID: 26308095

3. Hennen, S. et al. (2016) Scientific reports 6, 26236. PMID: 27196125

4. Song, G. et al. (2017) Nature 546, 312-315. PMID: 28514449

5. van Eyll, B. et al. (1994) FEBS letters 348, 7-13. PMID: 7517895

6. Graziano, MP. et al. (1993) Biochemical and biophysical research communications 196, 141-6. PMID: 8216285

7. Thorens, B. et al. (1993) Diabetes 42, 1678-82. PMID: 8405712

Note

For research use only.

Isotype Control

Mouse IgG2a (Fc Silence) Recombinant Isotype Control (MOPC 173) (MF533023)

Images

SDS-PAGE

SDS-PAGE for Anti-Human GLP1R Antibody (SAA0519).

References

Datasheet

Anti-Human GLP-1R Recombinant Antibody (SAA0519).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-Human GLP-1R Recombinant Antibody (SAA0519) (HW328013)

Overview

Images

References

Datasheet

SDS