Anti-Human GORASP2 Polyclonal Antibody (HP568014)

Name: Anti-Human GORASP2 Polyclonal Antibody
Brand: abinScience
SKU: HP568014
Price: 168 USD
Availability: InStock

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SDS

Overview

Catalog No.

HP568014

Description

Anti-Human GORASP2 Polyclonal Antibody (HP568014) is a rabbit polyclonal antibody detecting GORASP2 in ELISA, IHC, WB. Suitable for Human, Mouse, and Rat.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

Species reactivity

Human, Mouse, Rat

Applications

ELISA, IHC, WB

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human GORASP2 (Phe36-Glu208).

Target

GRS2, Golgi reassembly-stacking protein of 55 kDa, GOLPH6, p59, GORASP2, Golgi phosphoprotein 6, GRASP55, Golgi reassembly-stacking protein 2

Purification

Purified by antigen affinity column.

Accession

Q9H8Y8

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Golgi reassembly-stacking protein 2 (GORASP2) is a ~47 kDa protein. Key structural protein of the Golgi apparatus. The membrane cisternae of the Golgi apparatus adhere to each other to form stacks, which are aligned side by side to form the Golgi ribbon. Acting in concert with GORASP1/GRASP65, is required for the formation and maintenance of the Golgi ribbon, and may be dispensable for the formation of stacks. However, other studies suggest that GORASP2 plays a role in the assembly and membrane stacking of the Golgi cisternae, and in the process by which Golgi stacks reform after breakdown during mitosis and meiosis. May regulate the intracellular transport and presentation of a defined set of transmembrane proteins, such as transmembrane TGFA.

1. Zhang, Y. et al. (2021) The Journal of cell biology 220. PMID: 33301566

2. Shorter, J. et al. (1999) The EMBO journal 18, 4949-60. PMID: 10487747

3. Truschel, ST. et al. (2011) The Journal of biological chemistry 286, 20125-9. PMID: 21515684

4. Truschel, ST. et al. (2012) The Journal of biological chemistry 287, 19870-5. PMID: 22523075

5. Kuo, A. et al. (2000) The EMBO journal 19, 6427-39. PMID: 11101516

6. Gee, HY. et al. (2011) Cell 146, 746-60. PMID: 21884936

7. Kim, J. et al. (2016) Traffic (Copenhagen, Denmark) 17, 733-53. PMID: 27062250

8. Piao, H. et al. (2017) Scientific reports 7, 39887. PMID: 28067262

Note

For research use only.

Images

References

Datasheet

Anti-Human GORASP2 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-Human GORASP2 Polyclonal Antibody (HP568014)

Overview

Images

References

Datasheet

SDS

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