

| Catalog No. | HS846014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Species reactivity | Human, Mouse, Rat | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Host species | Rabbit | ||||||||
| Isotype | IgG | ||||||||
| Clonality | Polyclonal | ||||||||
| Immunogen | E. coli - derived recombinant Human GPAT3 (Ser207-Ser434). | ||||||||
| Target | 1-acyl-sn-glycerol-3-phosphate O-acyltransferase 9, AGPAT 10, 1-AGPAT 9, GPAT-3, hGPAT3, Glycerol-3-phosphate acyltransferase 3, Lysophosphatidic acid acyltransferase theta, 1-acyl-sn-glycerol-3-phosphate O-acyltransferase 10, LPAAT-theta, Acyl-CoA:glycerol-3-phosphate acyltransferase 3, 1-AGP acyltransferase 9, Lung cancer metastasis-associated protein 1, MAG1, MAG-1, GPAT3, AGPAT9 | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Accession | Q53EU6 | ||||||||
| Form | Liquid | ||||||||
| Storage buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Background | Glycerol-3-phosphate acyltransferase 3 (GPAT3) is a ~48 kDa protein. Converts glycerol-3-phosphate to 1-acyl-sn-glycerol-3-phosphate (lysophosphatidic acid or LPA) by incorporating an acyl moiety at the sn-1 position of the glycerol backbone. Also converts LPA into 1,2-diacyl-sn-glycerol-3-phosphate (phosphatidic acid or PA) by incorporating an acyl moiety at the sn-2 position of the glycerol backbone. Protects cells against lipotoxicity. 1. Cao, J. et al. (2006) Proceedings of the National Academy of Sciences of the United States of America 103, 19695-700. PMID: 17170135 2. Sukumaran, S. et al. (2009) Journal of molecular endocrinology 42, 469-78. PMID: 19318427 3. Piccolis, M. et al. (2019) Molecular cell 74, 32-44.e8. PMID: 30846318 | ||||||||
| Note | For research use only. |

Western blot analysis was performed using anti-Human GPAT3 polyclonal antibody at 1ug/mL on recombinant Human GPAT3 (Catalog No. HS846012).
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