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Anti-Human GPR143 Polyclonal Antibody (HA680014)

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Overview
Catalog No.HA680014
Description
Anti-Human GPR143 Polyclonal Antibody (HA680014) is a rabbit polyclonal antibody detecting G-protein coupled receptor 143; Ocular albinism type 1 protein; GPR143; OA1 in ELISA, IHC, WB. Suitable for Human.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
Species reactivityHuman
ApplicationsELISA, IHC, WB
Host speciesRabbit
IsotypeIgG
Clonality Polyclonal
Immunogen E. coli - derived recombinant human GPR143 (Trp313-Leu404).
Target G-protein coupled receptor 143; Ocular albinism type 1 protein; GPR143; OA1
Endotoxin level Please contact with the lab for this information.
Purification Purified by antigen affinity column.
Accession P51810
Form Liquid
Storage buffer 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Product Usage Information
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Stability and Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Background

G-protein coupled receptor 143 (GPR143) is a ~43 kDa protein. Receptor for tyrosine, L-DOPA and dopamine. After binding to L-DOPA, stimulates Ca(2+) influx into the cytoplasm, increases secretion of the neurotrophic factor SERPINF1 and relocalizes beta arrestin at the plasma membrane; this ligand-dependent signaling occurs through a G(q)-mediated pathway in melanocytic cells. Its activity is mediated by G proteins which activate the phosphoinositide signaling pathway. Also plays a role as an intracellular G protein-coupled receptor involved in melanosome biogenesis, organization and transport.

Note For research use only
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Formula
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V₁ (Stock Vol.)
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Working Solution
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Anti-Human GPR143 Polyclonal Antibody

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