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Anti-Human HAX1 Polyclonal Antibody (HT402014)

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Overview
Catalog No.HT402014
Species reactivityHuman
ApplicationsELISA, IHC, WB
Host speciesRabbit
ClonalityPolyclonal
IsotypeIgG
Immunogen E. coli - derived recombinant Human HAX1 (Lys205-Asp246).
Target HS1BP1, HS1-binding protein 1, HAX1, HSP1BP-1, HCLS1-associated protein X-1, HS1-associating protein X-1, HAX-1
Purification Purified by antigen affinity column.
Accession O00165
Form Liquid
Storage buffer 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Product Usage Information
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Stability and Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Background

HCLS1-associated protein X-1 (HAX1) is a ~31 kDa protein. Recruits the Arp2/3 complex to the cell cortex and regulates reorganization of the cortical actin cytoskeleton via its interaction with KCNC3 and the Arp2/3 complex. Slows down the rate of inactivation of KCNC3 channels. Promotes GNA13-mediated cell migration. Involved in the clathrin-mediated endocytosis pathway. May be involved in internalization of ABC transporters such as ABCB11.

1. Zhang, Y. et al. (2016) Cell 165, 434-448. PMID: 26997484
Note For research use only.
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Anti-Human HAX1 Polyclonal Antibody

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