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Anti-Human HB-EGF Recombinant Antibody (KM3566) (HV265023)

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Overview
Catalog No.HV265023
Description
Anti-Human HB-EGF Recombinant Antibody (KM3566) (HV265023) is a human monoclonal antibody detecting HB-EGF in ELISA, FCM, Functional assay. Suitable for Human.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
Species reactivityHuman
ApplicationsELISA, FCM, Functional assay
Host speciesHuman
ClonalityMonoclonal
IsotypeIgG1, kappa
Clone IDKM3566
Target DT-R, DTR, DTS, Diphtheria toxin receptor, HB-EGF, HBEGF, HEGFL, Heparin-binding EGF-like growth factor, Proheparin-binding EGF-like growth factor
Endotoxin level < 10 EU/mg as determined by LAL method.
Purity >95% as determined by SDS-PAGE.
Purification Protein A/G purified from cell culture supernatant.
Accession Q99075
Form Liquid
Storage buffer 0.01M PBS pH 7.4.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information
Application Dilution
ELISA 1:2000-1:20000
Stability and Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Background

Proheparin-binding EGF-like growth factor (HBEGF) is a ~23 kDa protein. Growth factor that mediates its effects via EGFR, ERBB2 and ERBB4. Required for normal cardiac valve formation and normal heart function. Promotes smooth muscle cell proliferation. May be involved in macrophage-mediated cellular proliferation. It is mitogenic for fibroblasts, but not endothelial cells.

Note For research use only.
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Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
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Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
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V₁ (Stock Vol.)
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Working Solution
C₂ (Working Conc.)
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V₂ (Working Vol.)
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