Anti-Human HCN2 Polyclonal Antibody (HP198014)

Name: Anti-Human HCN2 Polyclonal Antibody
Brand: abinScience
SKU: HP198014
Price: 168 USD
Availability: InStock

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SDS

Overview

Catalog No.

HP198014

Species reactivity

Human, Mouse, Rat

Applications

ELISA, IHC, WB

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human HCN2 (Gly524-Leu713).

Target

HCN2, Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2, BCNG-2, Brain cyclic nucleotide-gated channel 2, BCNG2

Purification

Purified by antigen affinity column.

Accession

Q9UL51

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (HCN2) is a ~96 kDa protein. Hyperpolarization-activated ion channel that is permeable to sodium and potassium ions. Displays lower selectivity for K(+) over Na(+) ions. Contributes to the native pacemaker currents in heart (If) and in neurons (Ih). Can also transport ammonium in the distal nephron. Involved in the initiation of neuropathic pain in sensory neurons.

1. Ludwig, A. et al. (1999) The EMBO journal 18, 2323-9. PMID: 10228147

2. Lolicato, M. et al. (2011) The Journal of biological chemistry 286, 44811-20. PMID: 22006928

3. Vaccari, T. et al. (1999) Biochimica et biophysica acta 1446, 419-25. PMID: 10524219

Note

For research use only.

Images

References

Datasheet

Anti-Human HCN2 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-Human HCN2 Polyclonal Antibody (HP198014)

Overview

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References

Datasheet

SDS

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