

| Catalog No. | HC466014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Species reactivity | Human, Mouse | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Host species | Rabbit | ||||||||
| Isotype | IgG | ||||||||
| Clonality | Polyclonal | ||||||||
| Immunogen | E. coli - derived recombinant Human HEPACAM (Arg73-Arg237). | ||||||||
| Target | HEPACAM, Protein hepaCAM, Hepatocyte cell adhesion molecule | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Accession | Q14CZ8 | ||||||||
| Form | Liquid | ||||||||
| Storage buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Background | Hepatic and glial cell adhesion molecule (HEPACAM) is a ~46 kDa protein. Involved in regulating cell motility and cell-matrix interactions. May inhibit cell growth through suppression of cell proliferation. In glia, associates and targets CLCN2 at astrocytic processes and myelinated fiber tracts where it may regulate transcellular chloride flux involved in neuron excitability. 1. Chung Moh, M. et al. (2005) Journal of hepatology 42, 833-41. PMID: 15885354 2. Moh, MC. et al. (2005) The Journal of biological chemistry 280, 27366-74. PMID: 15917256 3. Jeworutzki, E. et al. (2012) Neuron 73, 951-61. PMID: 22405205 | ||||||||
| Note | For research use only. |
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