Anti-Human HERPUD1 Polyclonal Antibody (HC651014)

Name: Anti-Human HERPUD1 Polyclonal Antibody
Brand: abinScience
SKU: HC651014
Price: 168 USD
Availability: InStock

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SDS

Overview

Catalog No.

HC651014

Species reactivity

Human, Mouse

Applications

ELISA, IHC, WB

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human HERPUD1 (Glu8-Asn87).

Target

HERPUD1, HERP, Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 1 protein, MIF1, KIAA0025, Methyl methanesulfonate (MMF)-inducible fragment protein 1

Purification

Purified by antigen affinity column.

Accession

Q15011

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 1 protein (HERPUD1) is a ~43 kDa protein. Component of the endoplasmic reticulum quality control (ERQC) system also called ER-associated degradation (ERAD) involved in ubiquitin-dependent degradation of misfolded endoplasmic reticulum proteins. Could enhance presenilin-mediated amyloid-beta protein 40 generation. Binds to ubiquilins and this interaction is required for efficient degradation of CD3D via the ERAD pathway.

1. Schulze, A. et al. (2005) Journal of molecular biology 354, 1021-7. PMID: 16289116

2. Schulz, J. et al. (2017) Journal of cell science 130, 3322-3335. PMID: 28827405

3. Kim, TY. et al. (2008) Biochemical and biophysical research communications 369, 741-6. PMID: 18307982

Note

For research use only.

Images

References

Datasheet

Anti-Human HERPUD1 Polyclonal Antibody.pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

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Anti-Human HERPUD1 Polyclonal Antibody (HC651014)

Overview

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References

Datasheet

SDS

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