

| Catalog No. | HB193014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Species reactivity | Human | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Host species | Rabbit | ||||||||
| Isotype | IgG | ||||||||
| Clonality | Polyclonal | ||||||||
| Immunogen | E. coli - derived recombinant Human HSD17B1 (Thr4-Pro289). | ||||||||
| Target | EDH17B1, Short chain dehydrogenase/reductase family 28C member 1, EDHB17, Placental 17-beta-hydroxysteroid dehydrogenase, SDR28C1, 20 alpha-hydroxysteroid dehydrogenase, 20-alpha-HSD, HSD17B1, 17-beta-HSD 1, E2DH, Estradiol 17-beta-dehydrogenase 1, EDH17B2, E17KSR, 17-beta-hydroxysteroid dehydrogenase type 1 | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Accession | P14061 | ||||||||
| Form | Liquid | ||||||||
| Storage buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Background | 17-beta-hydroxysteroid dehydrogenase type 1 (HSD17B1) is a ~34 kDa protein. Favors the reduction of estrogens and androgens. Converts estrone (E1) to a more potent estrogen, 17beta-estradiol (E2). Also has 20-alpha-HSD activity. Uses preferentially NADH. 1. Puranen, T. et al. (1997) Molecular endocrinology (Baltimore, Md.) 11, 77-86. PMID: 8994190 | ||||||||
| Note | For research use only. |
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