Anti-Human IA-2/PTPRN Recombinant Antibody (76F) (HS866013)

Name: Anti-Human IA-2/PTPRN Recombinant Antibody (76F)
Brand: abinScience
SKU: HS866013
Price: 191 USD
Availability: InStock

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100ug
1mg

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Overview
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References
Datasheet
SDS

Overview

Catalog No.

HS866013

Species reactivity

Human, Mouse, Rat

Applications

IHC, IP, WB

Host species

Mouse

Isotype

IgG2b, kappa

Clone ID

76F

Clonality

Monoclonal

Target

Receptor-type tyrosine-protein phosphatase-like N, R-PTP-N, Islet cell antigen 512, ICA 512, Islet cell autoantigen 3, PTP IA-2, ICA512-N-terminal fragment, ICA512-NTF, ICA512-transmembrane fragment, ICA512-TMF, ICA512-cleaved cytosolic fragment, ICA512-CCF, PTPRN, ICA3, ICA512

Endotoxin level

<10 EU/mg

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

Q16849

Form

Liquid

Storage buffer

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
WB	1:500-1:2000

Background

Receptor-type tyrosine-protein phosphatase-like N (IA-2/PTPRN) is a ~105 kDa protein. Plays a role in vesicle-mediated secretory processes. Required for normal accumulation of secretory vesicles in hippocampus, pituitary and pancreatic islets. Required for the accumulation of normal levels of insulin-containing vesicles and preventing their degradation. Plays a role in insulin secretion in response to glucose stimuli. Required for normal accumulation of the neurotransmitters norepinephrine, dopamine and serotonin in the brain.

1. Harashima, S. et al. (2012) Journal of diabetes investigation 3, 52-61. PMID: 24843546

Note

For research use only

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