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Anti-Human IA-2/PTPRN Recombinant Antibody (96/3) (HS866023)

Anti-Human IA-2/PTPRN Recombinant Antibody (96/3)
Anti-Human IA-2/PTPRN Recombinant Antibody (96/3)
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Overview
Catalog No.HS866023
Species reactivityHuman, Mouse, Rat
ApplicationsELISA, IHC, IP, WB
Host speciesMouse
IsotypeIgG2a, kappa
Clone ID96/3
Clonality Monoclonal
Target ICA 512, ICA3, ICA512, ICA512-CCF, ICA512-N-terminal fragment, ICA512-NTF, ICA512-TMF, ICA512-cleaved cytosolic fragment, ICA512-transmembrane fragment, Islet cell antigen 512, Islet cell autoantigen 3, PTP IA-2, PTPRN, R-PTP-N, Receptor-type tyrosine-protein phosphatase-like N
Endotoxin level Please contact with the lab for this information.
Purity >95% as determined by SDS-PAGE.
Purification Protein A/G purified from cell culture supernatant.
Accession Q16849, Q60673, Q63259
Form Liquid
Storage buffer 0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information
Application Dilution
ELISA 1:2000-1:20000
WB 1:500-1:2000
Stability and Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Background

Receptor-type tyrosine-protein phosphatase-like N (IA-2/PTPRN) is a ~105 kDa protein. Plays a role in vesicle-mediated secretory processes. Required for normal accumulation of secretory vesicles in hippocampus, pituitary and pancreatic islets. Required for the accumulation of normal levels of insulin-containing vesicles and preventing their degradation. Plays a role in insulin secretion in response to glucose stimuli. Required for normal accumulation of the neurotransmitters norepinephrine, dopamine and serotonin in the brain.

1. Harashima, S. et al. (2012) Journal of diabetes investigation 3, 52-61. PMID: 24843546
Note For research use only
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  • Anti-Human IA-2/PTPRN Recombinant Antibody (96/3)

    SDS-PAGE

    SDS-PAGE for Anti-Human IA-2/PTPRN Antibody (96/3)

References
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
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Formula
C₁ × V₁ = C₂ × V₂
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Stock Solution
C₁ (Stock Conc.)
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V₁ (Stock Vol.)
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Working Solution
C₂ (Working Conc.)
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