

| Catalog No. | HW405137 |
|---|---|
| Species reactivity | Human |
| Applications | ELISA, FCM |
| Host species | Mouse |
| Isotype | IgG2a, kappa |
| Clone ID | SAA2103 |
| Conjugation | APC |
| Clonality | Monoclonal |
| Target | Interferon gamma receptor 2, IFN-gamma receptor 2, IFN-gamma-R2, Interferon gamma receptor accessory factor 1, AF-1, Interferon gamma receptor beta-chain, IFN-gamma-R-beta, Interferon gamma transducer 1, IFNGR2, IFNGT1 |
| Endotoxin level | Please contact with the lab for this information. |
| Accession | P38484 |
| Form | Liquid |
| Storage buffer | 0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| Stability and Storage | Store at 4°C for 12 months. Protect from light. Do not freeze. |
| Background | Interferon gamma receptor 2 (IFNGR2) is a ~37 kDa protein. Associates with IFNGR1 to form a receptor for the cytokine interferon gamma (IFNG). Ligand binding stimulates activation of the JAK/STAT signaling pathway. Required for signal transduction in contrast to other receptor subunit responsible for ligand binding. 1. Sakatsume, M. et al. (1995) The Journal of biological chemistry 270, 17528-34. PMID: 7615558 2. Kotenko, SV. et al. (1995) The Journal of biological chemistry 270, 20915-21. PMID: 7673114 3. Soh, J. et al. (1994) Cell 76, 793-802. PMID: 8124716 4. Rosenzweig, SD. et al. (2004) Journal of immunology (Baltimore, Md. : 1950) 173, 3991-9. PMID: 15356148 |
| References | 1. Yang W, et al. Role of Azole Drugs in Promoting Fungal Cell Autophagy Revealed by an NIR Fluorescence-Based Theranostic Probe. Anal Chem. 2022 May 17;94(19):7092-7099. [HW405137] |
| Note | For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only. |




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