

| Catalog No. | HP940014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-Human IFT81 Polyclonal Antibody (HP940014) is a rabbit polyclonal antibody detecting IFT81 in ELISA, IHC, WB. Suitable for Human, Mouse, and Rat.
Highlights
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| Species reactivity | Human, Mouse, Rat | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Host species | Rabbit | ||||||||
| Clonality | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogen | E. coli - derived recombinant Human IFT81 (Met1-Lys124). | ||||||||
| Target | CDV1, IFT81, CDV-1, Carnitine deficiency-associated protein expressed in ventricle 1, Intraflagellar transport protein 81 homolog | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Accession | Q8WYA0 | ||||||||
| Form | Liquid | ||||||||
| Storage buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Background | Intraflagellar transport protein 81 homolog (IFT81) is a ~79 kDa protein. Component of the intraflagellar transport (IFT) complex B: together with IFT74, forms a tubulin-binding module that specifically mediates transport of tubulin within the cilium. Binds tubulin via its CH (calponin-homology)-like region. Required for ciliogenesis. Required for proper regulation of SHH signaling. Plays an important role during spermatogenesis by modulating the assembly and elongation of the sperm flagella. 1. Bhogaraju, S. et al. (2013) Science (New York, N.Y.) 341, 1009-12. PMID: 23990561 2. Duran, I. et al. (2016) Scientific reports 6, 34232. PMID: 27666822 | ||||||||
| Note | For research use only. |
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