



| Catalog No. | HV496023 | ||||
|---|---|---|---|---|---|
| Description |
Anti-Human IGHM Nanobody (SAA2369) [SAA2369] (HV496023) is a alpaca monoclonal antibody detecting IGHM in ELISA. Suitable for Human.
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| Species reactivity | Human | ||||
| Applications | ELISA | ||||
| Host species | Alpaca | ||||
| Isotype | VHH-8His | ||||
| Clone ID | SAA2369 | ||||
| Clonality | Monoclonal | ||||
| Target | IGHM | ||||
| Endotoxin level | Please contact with the lab for this information. | ||||
| Purity | >95% as determined by SDS-PAGE. | ||||
| Purification | Purified by Nickel column | ||||
| Accession | P01871 | ||||
| Form | Liquid | ||||
| Storage buffer | 0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Reconstitution | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. | ||||
| Product Usage Information |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||
| Background | Immunoglobulin heavy constant mu (IGHM) is a ~51 kDa protein. Constant region of immunoglobulin heavy chains. Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens. The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain. 1. Schroeder, HW. et al. (2010) The Journal of allergy and clinical immunology 125, S41-52. PMID: 20176268 2. McHeyzer-Williams, M. et al. (2011) Nature reviews. Immunology 12, 24-34. PMID: 22158414 3. Teng, G. et al. (2007) Annual review of genetics 41, 107-20. PMID: 17576170 | ||||
| Note | For research use only |

SDS-PAGE for Anti-Human IGHM Nanobody (SAA2369)

Detects IgM (Catalog No: HV496011) in indirect ELISA.




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