Anti-Human IL-13 Recombinant Antibody (SAA2016) (HW632013)

Name: Anti-Human IL-13 Recombinant Antibody (SAA2016)
Brand: abinScience
SKU: HW632013
Price: 110 USD
Availability: InStock

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1mg

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Overview
Images
References
Datasheet
SDS

Overview

Catalog No.

HW632013

Species reactivity

Human

Applications

ELISA, WB

Host species

Human

Isotype

IgG4, kappa

Clone ID

SAA2016

Clonality

Monoclonal

Tested applications

Target

IL13, NC30, Interleukin-13, IL-13

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P35225

RRID

Anti-Human IL13 Antibody (SAA2016) (abinScience Cat# HW632013, RRID:AB_3727928)
_x005F_x000D_

Form

Liquid

Storage buffer

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:2000-1:20000
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Background

Interleukin-13 (IL13) is a ~15 kDa protein. Cytokine that plays important roles in allergic inflammation and immune response to parasite infection. Synergizes with IL2 in regulating interferon-gamma synthesis. Stimulates B-cell proliferation, and activation of eosinophils, basophils, and mast cells. Plays an important role in controlling IL33 activity by modulating the production of transmembrane and soluble forms of interleukin-1 receptor-like 1/IL1RL1. Displays the capacity to antagonize Th1-driven proinflammatory immune response and downregulates synthesis of many proinflammatory cytokines including IL1, IL6, IL10, IL12 and TNF through a mechanism that partially involves suppression of NF-kappa-B.

1. Minty, A. et al. (1993) Nature 362, 248-50. PMID: 8096327

2. McKenzie, AN. et al. (1993) Proceedings of the National Academy of Sciences of the United States of America 90, 3735-9. PMID: 8097324

3. Defrance, T. et al. (1994) The Journal of experimental medicine 179, 135-43. PMID: 7903680

4. Luttmann, W. et al. (1996) Journal of immunology (Baltimore, Md. : 1950) 157, 1678-83. PMID: 8759755

5. Schnyder, B. et al. (1996) Blood 87, 4286-95. PMID: 8639787

6. Miloux, B. et al. (1997) FEBS letters 401, 163-6. PMID: 9013879

7. Kasaian, MT. et al. (2011) Journal of immunology (Baltimore, Md. : 1950) 187, 561-9. PMID: 21622864

Note

For research use only.

Images

Bioactivity

SEC-HPLC detection for Anti-Human IL13 Antibody (ABS1981).
SDS-PAGE

SDS-PAGE for Anti-Human IL13 Antibody (SAA2016).
Western blot

Western blot analysis was performed using anti-IL13 monoclonal antibody at 1μg/ml on various samples.
Lane 1: recombinant human IL13 (Catalog No: HW632012), 50ng
Lane 2: recombinant human IL13 (Catalog No: HW632012), 30ng
Lane 3: recombinant human IL13 (Catalog No: HW632012), 20ng