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Anti-Human IL21 Recombinant Antibody (SAA0390), PE (HV658127)

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Overview

Catalog No.	HV658127
Description	Anti-Human IL21 Antibody (SAA0390), PE [SAA0390] (HV658127) is a mouse monoclonal antibody detecting IL21 in ELISA, FCM. Suitable for Human. Highlights ●Flow Cytometry — Validated for flow cytometry applications.
Species reactivity	Human
Applications	ELISA, FCM
Host species	Mouse
Isotype	IgG1, kappa
Clone ID	SAA0390
Conjugation	PE
Clonality	Monoclonal
Target	IL-21, Interleukin-21, IL21, Za11
Endotoxin level	Please contact with the lab for this information.
Accession	Q9HBE4
Form	Liquid
Storage buffer	0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Store at 4°C for 12 months. Protect from light. Do not freeze.
Background	Interleukin-21 (IL21) is a ~18 kDa protein. Cytokine with immunoregulatory activity. May promote the transition between innate and adaptive immunity. Induces the production of IgG(1) and IgG(3) in B-cells. Implicated in the generation and maintenance of T follicular helper (Tfh) cells and the formation of germinal-centers. Together with IL6, control the early generation of Tfh cells and are critical for an effective antibody response to acute viral infection. 1. Parrish-Novak, J. et al. (2000) Nature 408, 57-63. PMID: 11081504 2. Strengell, M. et al. (2004) Journal of leukocyte biology 76, 416-22. PMID: 15178704
Note	For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.

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Datasheet

Anti-Human IL21 Recombinant Antibody (SAA0390), PE.pdf

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Anti-Human IL21 Recombinant Antibody (SAA0390), PE