Anti-Human IL21 Recombinant Antibody (SAA2070) (HV658013)

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Datasheet
SDS

Overview

Catalog No.

HV658013

Description

Anti-Human IL21 Antibody (SAA2070) [SAA2070] (HV658013) is a human monoclonal antibody detecting IL21 in ELISA, WB. Suitable for Human.

Species reactivity

Human

Applications

ELISA, WB

Host species

Human

Isotype

IgG1, kappa

Clone ID

SAA2070

Clonality

Monoclonal

Target

Interleukin-21, IL-21, Za11, IL21

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

Q9HBE4

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:2000-1:20000
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Interleukin-21 (IL21) is a ~18 kDa protein. Cytokine with immunoregulatory activity. May promote the transition between innate and adaptive immunity. Induces the production of IgG(1) and IgG(3) in B-cells. Implicated in the generation and maintenance of T follicular helper (Tfh) cells and the formation of germinal-centers. Together with IL6, control the early generation of Tfh cells and are critical for an effective antibody response to acute viral infection.

1. Parrish-Novak, J. et al. (2000) Nature 408, 57-63. PMID: 11081504

2. Strengell, M. et al. (2004) Journal of leukocyte biology 76, 416-22. PMID: 15178704

Note

For research use only.

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