Anti-Human IL22RA2 Polyclonal Antibody (HV100014)

Name: Anti-Human IL22RA2 Polyclonal Antibody
Brand: abinScience
SKU: HV100014
Price: 96 USD
Availability: InStock

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Spec:

20ug
50ug
100ug

Number:

Overview
Images
References
Datasheet
SDS

Overview

Catalog No.

HV100014

Species reactivity

Human

Applications

ELISA, IHC, WB

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human IL22RA2 (Thr22-Pro263).

Target

IL22RA2, Cytokine receptor family type 2, soluble 1, IL-22R-alpha-2, Cytokine receptor family 2 member 10, IL-22BP, CRF2-S1, Interleukin-22-binding protein, ZcytoR16, CRF2-10, Interleukin-22 receptor subunit alpha-2, IL22BP, Cytokine receptor class-II member 10, IL-22 receptor subunit alpha-2, IL-22RA2

Purification

Purified by antigen affinity column.

Accession

Q969J5

RRID

Anti-Human IL22RA2 Polyclonal Antibody (abinScience Cat# HV100014, RRID:AB_3722964)

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Interleukin-22 receptor subunit alpha-2 (IL22RA2) is a ~30 kDa protein. Isoform 2 is a receptor for IL22. Binds to IL22, prevents interaction with the functional IL-22R complex and blocks the activity of IL22 (in vitro). May play an important role as an IL22 antagonist in the regulation of inflammatory responses.

Note

For research use only.

Images

Immunofluorescence

HepG2 cells were fixed with 4% paraformaldehyde for 20 minutes, followed by blocking with 5% goat serum for 1 hour. The cells were then incubated with a primary antibody targeting IL22RA2 (HV100014) at a concentration of 29.2 ug/ml overnight at 4°C. Afterward, the cells were incubated with a secondary antibody, Goat Anti-Rabbit IgG (Alexa Fluor-488) for 50 minutes at room temperature. The localization of IL22RA2 was visualized (shown in green), and nuclear DNA was stained with DAPI (shown in blue).

References

Datasheet