Anti-Human IL-31RA Recombinant Antibody (SAA0825), PE (HV121127)

Name: Anti-Human IL-31RA Recombinant Antibody (SAA0825), PE
Brand: abinScience
SKU: HV121127
Price: 290 USD
Availability: InStock

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Overview
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Datasheet
SDS

Overview

Catalog No.	HV121127
Species reactivity	Human
Applications	ELISA, FCM
Host species	Human
Isotype	IgG2, kappa
Clone ID	SAA0825
Conjugation	PE
Clonality	Monoclonal
Tested applications	FCM
Target	IL-31RA, Interleukin-31 receptor subunit alpha, IL31RA, hGLM-R, ZcytoR17, IL-31R-alpha, GPL, CRL3, Cytokine receptor-like 3, IL-31R subunit alpha, IL-31 receptor subunit alpha, Gp130-like receptor, GLM-R, Gp130-like monocyte receptor
Endotoxin level	Please contact with the lab for this information.
Associated products	Human IgG2 Recombinant Isotype Control Antibody (HyHEL-10), PE
Accession	Q8NI17
Form	Liquid
Storage buffer	0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Store at 4°C for 12 months. Protect from light. Do not freeze.
Background	Interleukin-31 receptor subunit alpha (IL31RA) is a ~82 kDa protein. Associates with OSMR to form the interleukin-31 receptor which activates STAT3 and to a lower extent STAT1 and STAT5. May function in skin immunity. Mediates IL31-induced itch, probably in a manner dependent on cation channels TRPA1 and TRPV1. Positively regulates numbers and cycling status of immature subsets of myeloid progenitor cells in bone marrow in vivo and enhances myeloid progenitor cell survival in vitro. _x005F_x000D_ _x005F_x000D_ 1. Ghilardi, N. et al. (2002) The Journal of biological chemistry 277, 16831-6. PMID: 11877449 _x005F_x000D_ _x005F_x000D_ 2. Diveu, C. et al. (2003) The Journal of biological chemistry 278, 49850-9. PMID: 14504285 _x005F_x000D_ _x005F_x000D_ 3. Dreuw, A. et al. (2004) The Journal of biological chemistry 279, 36112-20. PMID: 15194700 _x005F_x000D_ _x005F_x000D_ 4. Diveu, C. et al. (2004) European cytokine network 15, 291-302. PMID: 15627637 _x005F_x000D_ _x005F_x000D_ 5. Dillon, SR. et al. (2004) Nature immunology 5, 752-60. PMID: 15184896
Note	For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.

Images

Flow CytoMetry

Flow-cytometry using PE anti-human IL31RA antibody. U87 cells were stained with an irrelevant antibody (Blue Histogram) or an PE anti-human IL31RA monoclonal antibody (Catalog: HV121127, Yellow Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, and cells analysed on a NovoCyte Flow Cytometer.

References

Datasheet