

| Catalog No. | HD173014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-Human INCA1 Polyclonal Antibody (HD173014) is a rabbit polyclonal antibody detecting Protein INCA1. Suitable for Human.
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| Species reactivity | Human | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Host species | Rabbit | ||||||||
| Isotype | IgG | ||||||||
| Clonality | Polyclonal | ||||||||
| Immunogen | E. coli - derived recombinant Human INCA1 (Gln2-Glu236). | ||||||||
| Target | INCA1, Inhibitor of CDK interacting with cyclin A1, Protein INCA1 | ||||||||
| Endotoxin level | Please contact with the lab for this information. | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Accession | Q0VD86 | ||||||||
| Form | Liquid | ||||||||
| Storage buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Background | Protein INCA1 is a ~26 kDa protein. Binds to CDK2-bound cyclins and inhibits the kinase activity of CDK2; binding to cyclins is critical for its function as CDK inhibitor. Inhibits cell growth and cell proliferation and may play a role in cell cycle control. Required for ING5-mediated regulation of S-phase progression, enhancement of Fas-induced apoptosis and inhibition of cell growth. 1. Bäumer, N. et al. (2011) The Journal of biological chemistry 286, 28210-22. PMID: 21540187 | ||||||||
| Note | For research use only |
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