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Anti-Human INCA1 Polyclonal Antibody (HD173014)

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Overview
Catalog No.HD173014
Description
Anti-Human INCA1 Polyclonal Antibody (HD173014) is a rabbit polyclonal antibody detecting Protein INCA1. Suitable for Human.
Species reactivityHuman
ApplicationsELISA, IHC, WB
Host speciesRabbit
IsotypeIgG
Clonality Polyclonal
Immunogen E. coli - derived recombinant Human INCA1 (Gln2-Glu236).
Target INCA1, Inhibitor of CDK interacting with cyclin A1, Protein INCA1
Endotoxin level Please contact with the lab for this information.
Purification Purified by antigen affinity column.
Accession Q0VD86
Form Liquid
Storage buffer 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Background

Protein INCA1 is a ~26 kDa protein. Binds to CDK2-bound cyclins and inhibits the kinase activity of CDK2; binding to cyclins is critical for its function as CDK inhibitor. Inhibits cell growth and cell proliferation and may play a role in cell cycle control. Required for ING5-mediated regulation of S-phase progression, enhancement of Fas-induced apoptosis and inhibition of cell growth.

1. Bäumer, N. et al. (2011) The Journal of biological chemistry 286, 28210-22. PMID: 21540187
Note For research use only
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Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
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Concentration
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Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
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V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
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V₂ (Working Vol.)
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