

| Catalog No. | HP004014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Species reactivity | Human, Mouse, Rat | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Host species | Rabbit | ||||||||
| Clonality | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogen | E. coli - derived recombinant Human ISYNA1 (Met1-Gly495). | ||||||||
| Target | hIPS, Myo-inositol 1-phosphate synthase, Inositol-3-phosphate synthase 1, INO1, ISYNA1, Myo-inositol 1-phosphate synthase A1, MIP synthase, IPS 1, hINO1, MI-1-P synthase | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Accession | Q9NPH2 | ||||||||
| Form | Liquid | ||||||||
| Storage buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Background | Inositol-3-phosphate synthase 1 (ISYNA1) is a ~61 kDa protein. Key enzyme in myo-inositol biosynthesis pathway that catalyzes the conversion of glucose 6-phosphate to 1-myo-inositol 1-phosphate in a NAD-dependent manner. Rate-limiting enzyme in the synthesis of all inositol-containing compounds. 1. Ju, S. et al. (2004) The Journal of biological chemistry 279, 21759-65. PMID: 15024000 2. Deranieh, RM. et al. (2013) The Journal of biological chemistry 288, 26822-33. PMID: 23902760 | ||||||||
| Note | For research use only. |

Western blot analysis was performed using anti-ISYNA1 polyclonal antibody at 1μg/ml on various samples.
Lane 1: K562 cell lysate
Lane 2: HCT-116 cell lysate
Lane 3: Mouse testis lysate
Lane 4: Rat testis lysate
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