Anti-Human KCNK9 Recombinant Antibody (SAA1716) (HV232013)

Name: Anti-Human KCNK9 Recombinant Antibody (SAA1716)
Brand: abinScience
SKU: HV232013
Price: 196 USD
Availability: InStock

Datasheet Share product Copy info

Price(USD):

Spec:

50ug
100ug
1mg

Number:

Get quote

Overview
Images
References
Datasheet
SDS

Overview

Catalog No.

HV232013

Species reactivity

Human

Applications

ELISA

Host species

Mouse

Isotype

IgG2a, kappa

Clone ID

SAA1716

Clonality

Monoclonal

Target

TASK3, KCNK9, Acid-sensitive potassium channel protein TASK-3, Potassium channel subfamily K member 9, Two pore K(+) channel KT3.2, TWIK-related acid-sensitive K(+) channel 3, Two pore potassium channel KT3.2

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

Q9NPC2

RRID

Anti-Human KCNK9 Antibody (SAA1716) (abinScience Cat# HV232013, RRID:AB_3727477)

Form

Liquid

Storage buffer

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:2000-1:20000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Background

Potassium channel subfamily K member 9 (KCNK9) is a ~42 kDa protein. K(+) channel that conducts voltage-dependent outward rectifying currents upon membrane depolarization. Voltage sensing is coupled to K(+) electrochemical gradient in an 'ion flux gating' mode where outward but not inward ion flow opens the gate. Changes ion selectivity and becomes permeable to Na(+) ions in response to extracellular acidification. Protonation of the pH sensor His-98 stabilizes C-type inactivation conformation likely converting the channel from outward K(+)-conducting, to inward Na(+)-conducting to nonconductive state. Homo- and heterodimerizes to form functional channels with distinct regulatory and gating properties.

1. Chapman, CG. et al. (2000) Brain research. Molecular brain research 82, 74-83. PMID: 11042359

2. Vega-Saenz de Miera, E. et al. (2001) Journal of neurophysiology 86, 130-42. PMID: 11431495

3. Schewe, M. et al. (2016) Cell 164, 937-49. PMID: 26919430

4. Lin, H. et al. (2024) Proceedings of the National Academy of Sciences of the United States of America 121, e2320345121. PMID: 38630723

5. Ma, L. et al. (2012) The Journal of biological chemistry 287, 37145-53. PMID: 22948150

6. Plant, LD. et al. (2012) Science signaling 5, ra84. PMID: 23169818

Note

For research use only.

Images

SDS-PAGE

SDS-PAGE for Anti-Human KCNK9 Antibody (SAA1716)

References

Datasheet

Anti-Human KCNK9 Recombinant Antibody (SAA1716).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-Human KCNK9 Recombinant Antibody (SAA1716) (HV232013)

Overview

Images

References

Datasheet

SDS

Quick access

Contact Us